Molecule Details

Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2CC(=O)N2)c1
3-aminopyridine-like Assayed
View on Fragalysis x10789
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2CC(=O)N2)c1
MW: 345.09
Fraction sp3: 0.24
HBA: 4
HBD: 2
Rotatable Bonds: 5
TPSA: 80.32
cLogP: 2.45
Covalent Warhead:
Covalent Fragment: ✔️
Activity Data
IC50 (µM) - Fluorescence: 3.6098563119233
IC50 (µM) - RapidFire: 0.940748777754165
Trypsin IC50 (µM): 99.0
pIC50 (µM) - Fluorescence 5.44251008457101
Average Inhibition @ 20 µM - Fluorescence: 94.4703
Average Inhibition @ 50 µM - Fluorescence: 97.00562
Average Inhibition @ 50 µM - RapidFire: 87.191315835
Relative Solubility @ 20 µM: 0.99
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-10

betalactam

b-lactam

Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-7
1.000

View
Cc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-1
0.744

View
COc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-5
0.734

View
CCc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-6
0.734

View
Cc1ccncc1NC(=O)Cc1cc(F)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-2
0.725

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2COC2)c1

WIL-MOD-03b86a88-4
0.700

View
C#Cc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-4
0.699

View
Cc1ccncc1NC(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-6
0.699

View
Cc1ccncc1NC(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-3
0.699

View
COc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

MAT-POS-c9973a83-1
0.680

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

BRU-LEF-c49414a7-1
0.654

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-7
0.654

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

EDJ-MED-7320d5d2-1
0.611

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

ALP-POS-3b848b35-2
0.611

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

MAT-POS-3b92565d-3
0.611

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)c(OC2CC(=O)N2)c1

RAL-THA-901e9a10-8
0.605

View
Cc1ccncc1NC(=O)N(C)c1cc(Cl)cc(OC2CC(=O)N2)c1

MAR-UCB-ad2ff052-1
0.591

View
CCN(C(=O)Nc1cnccc1C)c1cc(Cl)cc(OC2CC(=O)N2)c1

MAR-UCB-ad2ff052-2
0.589

View
Cc1ccncc1NC(=O)C(C)c1cc(Cl)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-8
0.586

View
Cn1cc(NC(=O)Cc2cc(Cl)cc(OC3CC(=O)N3)c2)c2ccccc2c1=O

MAT-POS-3b92565d-9
0.582

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OCc2ncc[nH]2)c1

RAL-THA-6b94ceba-1
0.573

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OCc2cnc[nH]2)c1

RAL-THA-6b94ceba-3
0.573

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OCc2ccn[nH]2)c1

RAL-THA-6b94ceba-4
0.573

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OCc2ncn[nH]2)c1

RAL-THA-6b94ceba-2
0.567

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C2COC2)c1

WIL-MOD-03b86a88-2
0.553

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-3b92565d-6
0.548

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(C)C(N)=O)c1

WIL-MOD-03b86a88-3
0.548

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(N)=O)c1

RAL-THA-6b94ceba-6
0.537

View
CCCCC(C(=O)Nc1cnccc1C)c1cc(Cl)cc(OC2CC(=O)N2)c1

JAN-GHE-f4ca5a00-15
0.536

View
Cc1ccncc1NC(=O)N(CCC1CCCCC1)c1cc(Cl)cc(OC2CC(=O)N2)c1

MAR-UCB-ad2ff052-3
0.530

View
Cc1ccncc1NC(=O)N(CCC1CCCCC1)c1cc(Cl)cc(OC2CC(=O)N2)c1

DAR-DIA-1d7f034a-1
0.530

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CNS(C)(=O)=O)c1

RAL-THA-6b94ceba-12
0.529

View
CNS(=O)(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-14
0.529

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(C)(=O)=O)c1

WIL-MOD-03b86a88-5
0.529

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2cnc[nH]2)c1

RAL-THA-6b94ceba-11
0.529

View
Cc1ccncc1NC(=O)C(CCc1ccccc1)c1cc(Cl)cc(OC2CC(=O)N2)c1

ALP-POS-3fc1724e-6
0.525

View
CNC(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-7
0.524

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(S(N)(=O)=O)c1

RAL-THA-6b94ceba-13
0.524

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(N)(=O)=O)c1

WIL-MOD-03b86a88-6
0.523

View
COC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-8
0.523

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1nc2ccccc2[nH]1

ALP-POS-a30bcdb4-1
0.521

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CS(N)(=O)=O)c1

RAL-THA-6b94ceba-15
0.518

View
CC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-5
0.518

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2ncc[nH]2)c1

RAL-THA-6b94ceba-9
0.517

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2nnc[nH]2)c1

RAL-THA-6b94ceba-10
0.517

View
CNS(=O)(=O)Cc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-16
0.512

View
O=C(Cc1cc(Cl)cc(OC2CCC(=O)N2)c1)Nc1cncc2ccccc12

MAT-POS-9ff17035-1
0.510

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.506

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.506

View
Cc1ccncc1NC(=O)C(CCC1CCCCC1)c1cc(Cl)cc(OC2CC(=O)N2)c1

ALP-POS-3fc1724e-5
0.505

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.500

View
O=C1CC(Oc2cc(Cl)cc(CC(=O)Nn3cnc4ccccc43)c2)N1

MAT-POS-c478e61b-1
0.465

View
O=C1CC(Oc2cc(Cl)cc(CC(=O)Nn3cnc4ccccc43)c2)N1

MAT-POS-3b92565d-12
0.465

View
COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.464

View
Cc1ccncc1NC(=O)Cc1cc(Cl)c2c(c1)OCCO2

BAR-COM-0f94fc3d-28
0.462

View
O=C1CC(Oc2cc(Cl)cc(CC(=O)Nn3cnc4ccccc4c3=O)c2)N1

JAN-GHE-74b8b0cb-1
0.460

View
Cc1ccncc1NC(=O)Cc1cccc(C2CC2)c1

ALP-POS-95b75b4d-4
0.460

View
Cc1ccncc1CC(=O)Nc1cc(C#N)cc(OC2CC(=O)N2)c1

TRY-UNI-bbd40bb4-2
0.448

View
Cc1ccncc1NC(=O)Nc1ccc(OC2CC(=O)N2)s1

TRY-UNI-bbd40bb4-6
0.446

View
Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5
0.443

View
Cc1ccc(CC(=O)Nc2cnccc2C)cc1

JAN-GHE-83b26c96-11
0.443

View
Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.443

View
Cc1ccncc1NC(=O)CCOC1CC1

MAT-POS-590ac91e-10
0.439

View
Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

VLA-UCB-00f2c2b3-2
0.438

View
Cc1ccncc1NC(=O)Cc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-3
0.433

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.429

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.429

View
Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.429

View
Cc1ccncc1NC(=O)Cc1ccsc1

MIH-UNI-6b9ca91a-1
0.427

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.424

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.424

View
Cc1ccncc1NC(=O)Cc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-2
0.422

View
Cc1ccncc1NC(=O)Cc1cnn(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-62
0.422

View
Cc1cc(CC(=O)Nc2cnccc2C)[nH]n1

EDJ-MED-c9f55a56-1
0.422

View
CCCCOc1ccc(Cl)cc1CC(=O)Nc1cnccc1C

EDG-MED-0da5ad92-7
0.419

View
Cc1ccncc1NC(=O)Cc1ccc2[nH]ccc2c1

VLA-UCB-00f2c2b3-1
0.418

View
Cc1ccncc1NC(=O)Cc1cccc([S+](C)[O-])c1

DAR-DIA-0cde14eb-78
0.416

View
Cc1ccncc1NC(=O)Cc1cccc(C(C)(F)F)c1

DAR-DIA-0cde14eb-79
0.416

View
Cc1ccncc1NC(=O)Cc1cc(N2CCCCC2)cc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-17
0.414

View
Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.413

View
Cc1ccncc1NC(=O)Cc1ccc2nc[nH]c2c1

GAB-REV-70cc3ca5-18
0.413

View
Cc1ccncc1NC(=O)Cc1cc(N2CCCCC2)cc(C2(C)CC2)c1

DAR-DIA-0cde14eb-16
0.412

View
Cc1ccncc1NC(=O)Cc1ccc(S(N)(=O)=O)cc1

GAB-REV-70cc3ca5-20
0.412

View
Cc1ccncc1NC(=O)Cc1cnn(C2(C)CC2)c1

DAR-DIA-0cde14eb-61
0.411

View
Cc1ccncc1NC(=O)Cc1cnn(C2(I)CC2)c1

DAR-DIA-0cde14eb-64
0.411

View
Cc1ccncc1NC(=O)Cc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-1
0.411

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
0.409

View
Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2
0.409

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.409

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.409

View
Cc1ccncc1NC(=O)Cc1cncc(C#N)c1

TRY-UNI-2eddb1ff-1
0.409

View
Cc1ccncc1NC(=O)Cc1cccc(-c2cn[nH]c2)c1

EDJ-MED-e58735b6-4
0.409

View
Cc1ccncc1CN1C(=O)C(=O)c2ccc(-c3cc(Cl)cc(OC4CC(=O)N4)c3)cc21

DAR-DIA-53551c05-7
0.407

View
Cc1ccncc1NC(=O)Cc1cnn(C2(F)CC2)c1

DAR-DIA-0cde14eb-63
0.407

View
Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-20
0.404

View
Cc1ccncc1NC(=O)Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-4
0.404

View
O=C(Cc1cncc2ccccc12)Nc1cc(Cl)cc(OC2CC(=O)N2)c1

ERI-UCB-ce40166b-5
0.404

View
Cc1ccncc1NC(=O)Cc1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-4
0.402

View
Cc1ccncc1NC(=O)Cc1cc(N2CCCCC2)cc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-29
0.402

View
Cc1ccncc1NC(=O)Cc1cccc(S(N)(=O)=O)c1

EDJ-MED-e58735b6-3
0.400

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC(OC)=C1

0.526

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.500

View
CC1=CC=NC=C1NC(=O)COC1=CC(Cl)=CC(Cl)=C1

0.494

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC(OC)=C1OC

0.494

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC(OC)=C1O

0.494

View
CC1=CC(C)=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.494

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=C1

0.487

View
CC1=CC=NC=C1NC(=O)CC1CC(=O)N1

0.481

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2CC2)=C1

0.478

View
CC1=CC=NC=C1NC(=O)CC1=CC=NC=C1

0.474

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.473

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C(Cl)=C1

0.469

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC=C1Cl

0.465

View
COC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.464

View
COC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1OC

0.464

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=N1

0.463

View
CC1=CC=NC=C1NC(=O)CC1=CC(Cl)=C2OCCOC2=C1

0.462

View
CC1=CC=NC=C1NC(=O)CC1=CN=CN=C1

0.462

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OC(F)F)=C1

0.460

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(C2CC2)=C1

0.460

View
CCOC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.458

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC=C1C

0.458

View
COC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.457

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)N=C1

0.457

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C(N)=O)C=C1

0.457

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(O)C=C1

0.456

View
COC1=CC=C(Cl)C=C1CC(=O)NC1=CN=CC=C1C

0.453

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=CC(Cl)=C2)=C1

0.453

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Br)C(Cl)=C1

0.452

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1C

0.450

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(F)C=C1

0.450

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(I)C=C1

0.450

View
CC1=CC=NC=C1NC(=O)CC1=CC(OC(C)C)=CC=C1

0.448

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(OC(F)F)C=C1

0.447

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=C(Cl)C=C2)=C1

0.447

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(F)C(F)=C1

0.446

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OC(F)(F)F)=C1

0.443

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.443

View
CC1=CC=NC=C1NC(=O)CC1=CC=CN=C1

0.443

View
CC1=CC=NC=C1NC(=O)COC1=CC=CC(Cl)=C1

0.442

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=C1Cl

0.440

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2CC(=O)NC2=C1

0.440

View
CC1=CC=NC=C1NC(=O)CC1=C(Cl)C=CC=C1Cl

0.439

View
CC1=CN=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.439

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1O

0.439

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1Br

0.439

View
CCC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.438

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Br)C=C1

0.438

View
COC1=CC=C(CC(=O)NC2=CN=CC=C2C)C(Cl)=C1

0.437

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2CCCCC2=C1

0.437

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(NC(=O)C2CC2)C=C1

0.437

View
CC1=CC=NC=C1NC(=O)CC1=CC(Cl)=CC=C1Cl

0.435

View
CC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.434

View
CC1=CC=NC=C1NC(=O)CC1=CN=CC(O)=C1

0.434

View
CCCOC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.433

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(CN)C=C1

0.432

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2CCCC2=C1

0.432

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=C1Br

0.430

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(OC(F)(F)F)C=C1

0.430

View
CC1=CC=NC=C1NC(=O)CC1=CC(Cl)=CC2=C1OCC2

0.430

View
COCCOC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.429

View
CC1=CC=NC=C1NC(=O)COC1=CC=C(Cl)C=C1

0.429

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(I)=C1

0.429

View
CC1=CC=NC=C1NC(=O)CC1=C(Cl)C=CC=C1C

0.429

View
CC1=CC=NC=C1NC(=O)CC1=CN=CC=C1Cl

0.427

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2C=CC=CC2=C1

0.425

View
CC1=CC=NC=C1NC(=O)CC1=CC(Cl)=CC=C1Br

0.425

View
CNC(=O)COC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.424

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC(F)(F)F)=C1

0.424

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC#N)=C1

0.424

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Br)=C1

0.424

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=CC=C2Cl)=C1

0.423

View
CC1=CC=NC=C1NC(=O)CCOC1=CC=CC(Cl)=C1

0.422

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2[NH]C(=O)[NH]C2=C1

0.422

View
CC1=CC=NC=C1NC(=O)CC1=CN=C2C=CC=CC2=C1

0.422

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(OCC(C)C)C=C1

0.420

View
COCC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.420

View
COCCOC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.420

View
CC(C)=CCOC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.419

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC=C1Cl

0.417

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2OCCOC2=C1

0.416

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2OCOC2=C1

0.416

View
CC1=CC(C)=C(CC(=O)NC2=CN=CC=C2C)C(C)=C1

0.415

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(NC(=O)OC(C)(C)C)C=C1

0.411

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=CN=C2)=C1

0.411

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C2=CC=CC=C2)C=C1

0.407

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2COCC2=C1

0.407

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCCCOC2=CC=CC=C2)=C1

0.406

View
CC1=CC=CC=C1COC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.402

View
CC1=CC=CC(COC2=CC=CC(CC(=O)NC3=CN=CC=C3C)=C2)=C1

0.402

View
COC1=CC(CC(=O)NC2=CC=CC=C2OC2CC(=O)N2)=CC(OC)=C1

0.398

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2OCCC2=C1

0.398

View
CC1=CC=NC=C1NC(=O)CC1=C(F)C=CC=C1Cl

0.393

View
CC1=CC(C)=CC(CC(=O)NC2=CC=CC=C2OC2CC(=O)N2)=C1

0.391

View
CC1=CC(C)=CC(CC(=O)NC2=CC=C(OC3CC(=O)N3)C=C2)=C1

0.389

View
COC1=CC(CC(=O)NC2=CC=C(OC3CC(=O)N3)C=C2)=CC(OC)=C1

0.385

View
CC1=CC=NC=C1NC(=O)CC1=C(C)N(C2=CC=C(Cl)C=C2)N=C1C

0.371

View
CC1=CC=NC=C1NC(=O)CNC(=O)CC1=CC=CC=C1

0.360

View
COC1=CC(CC(=O)NC2=CC=NC=C2C)=CC(OC)=C1

0.352

View
CC1=CC(C)=C(CC(=O)NC2=CC=C(OC3CC(=O)N3)C=C2)C(C)=C1

0.351

View

C(NC1=C(C)C=CN=C1)(=O)CC1C=CC=C(OC)C=1

0.464

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=C(OCC)C=C1

0.458

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=C(OCCCCC)C=C1

0.432

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=C(OCC(C)C)C=C1

0.420

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=C(OC(N(C)C)=O)C=C1

0.420

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1C=CC=C(OC)C=1

0.299

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=C(OCC)C=C1

0.281

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=C(OC)C=C1

0.274

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=C(OCC(C)C)C=C1

0.255

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=C(OC(N(C)C)=O)C=C1

0.255

View


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